This species appears to be widespread and common (Luna-Vega 2001) although it may not be abundant (Steege and Cornelissen 1989, Damon and Roblero 2007). It is reported to be now scarce in Soconusco, Chiapas, indicating that the population may be declining (Damon and Roblero 2007). The size of the population is unknown.

This species is a warm to cool growing orchid, which is found in open humid evergreen to semi deciduous cloud forest, on tree trunks and larger branches from 900 to 2,400 m asl (Isope 2009). The taxon grows in a wide variety of habitats and is reported to occur within 15 different ecoregions (GIS data, specimen data). It is also reported to occur in lowland (wallaba) forest in Guyana (at less than 100 m asl) (De Steege and Cornelissen 1989). It flowers in the late spring through the early autumn. Pollination was observed but 0 fruit set in a five years study in Soconusco (Damon and Roblero 2007).

Brassia verrucosa is rated as Least Concern due to the very large geographic range, low habitat specificity and high adaptability, the fact that it is known from more than 100 locations and occurs over 15 ecoregions, and occurrence within numerous conservation units throughout its range. However due to low seed set and recruitment, high rate of habitat loss and degradation in the region, and additional threat of extraction of individuals from the wild for the horticultural trade and due to indication that the population may be declining, the current range and size of the population should be determined. The population should be monitored at regular intervals.

Brassia verrucosa is a very variable, large, pseudobulb, epiphytic orchid which occurs throughout Central and Northern South America. The taxon is reported to occur from Mexico to northern Brazil.

Epiphytes have experienced dramatic population decreases mainly because of habitat loss and extraction activities, which have driven many species close to extinction (Mondragon et al. 2006). Neotropical cloud forests are highly threatened ecosystems. Damage done to them is likely to be irreversible due to their low resilience to disturbance. These communities have been seriously disturbed for centuries by human activities such as forestry, road building, agriculture, farming, colonization, pastures and fires. The increasing human population has put pressures on these forests so that the disturbance is so extensive in several areas that the natural vegetation is disappearing quickly. Many of these forests today are restricted to inaccessible slopes and have been partially replaced by grasslands and croplands (Luna-Vega et al. 2001). This species is an attractive orchid with showy flowers, which is very popular in the horticultural trade. Orchids are often the prey of unscrupulous collectors (Cribb et al. 2003). Collecting from natural sources is still very common in parts of the range in spite of prohibitions of international commerce of species collected in the wild (Saddi et al. 2005).

This species has been collected within numerous conservation units throughout its range. This orchid is currently listed on Appendix II of the Convention on International Trade in Endangered Species (CITES).

The taxon is grown ex situ in various botanical institutions and by hobbyists. As with all orchids, the taxon should not be removed from the wild. Micropropagation protocols if they do not already exist should be established for this species.

Field surveys should be conducted to determine the current range and size of the population, as some collections date from more than 50 years. Representative samples of the population should be monitored at regular intervals to detect any changes in dynamics.