Ageratina altissima, or white snakeroot, is a common, widespread plant native to much of eastern North America. The name "snakeroot" refers to a traditional use to cure snakebites. White snakeroot is toxic and when consumed by cattle their milk and meat become contaminated. Consuming these products can cause "milk sickness", which killed thousands of people in the early 19th century including the mother of Abraham Lincoln, Nancy Hanks Lincoln.
Perennials, (30–)50–80(–120) cm (bases usually fibrous-rooted crowns, sometimes rhizomatous). Stems ascending to erect, sometimes semiscandent, puberulent (hairs minute, crisped). Leaves opposite; petioles (5–)10–30(–50) mm; blades usually deltate-ovate to ovate or broadly lanceolate, sometimes ovate-lanceolate, 4–11(–13) × 2.5–8(–9) cm, bases usually rounded to truncate or obtuse, sometimes cordate, margins coarsely and doubly incised-serrate, apices usually acuminate. Heads clustered. Peduncles 1–5 mm, puberulent. Involucres 4–5 mm. Phyllaries: apices acute, abaxial faces glabrous or sparsely and finely villous. Corollas white, lobes sparsely short-villous. Cypselae glabrous.